General Biology I
Master the full spectrum of foundational biological concepts from the chemical and molecular basis of life to genetic engineering.
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Embark on an in-depth exploration into the building blocks of life. This course aims to equip students with an understanding of key biological concepts, from the chemical foundation of life to advanced topics in biotechnology and genomics. Through a series of interactive virtual simulations, students will analyze cellular structures, decipher metabolic pathways, and explore the mechanisms of gene expression and inheritance.
Investigating the Building Blocks of Life
Examine and differentiate the essential elements that constitute life, starting with the chemical foundations and biological macromolecules. Apply this knowledge and utilize virtual labs to reveal cellular structures and functions, which in turn, facilitate exploring complex, but essential, cellular processes such as respiration, photosynthesis, and division that power life.
Traverse the Path from DNA to Biotechnology
Walk the path that begins with Mendel’s Laws, the foundation of our knowledge of traits and inheritance. Assess Mendel’s experiments and extend this understanding to modern genetics, examining the structure and function of DNA, and the processes by which genes are expressed and proteins synthesized. Finally, apply theory in our genomics and biotechnology labs to see how genes and genetic processes can be leveraged to impact society and medicine.
Learning Objectives
- Illustrate and contextualize the chemical and molecular foundations of life
- Apply principles of metabolism, cellular respiration, and photosynthesis in energetic contexts
- Understand mechanisms of cell communication, reproduction, and genetic inheritance
- Evaluate advancements in biotechnology and genomics, considering their ethical, social, and practical implications
Browse Course Simulations by Unit
Link
The Study of Life
Pipetting: Selecting and Using Micropipettes
Pipetting: Master the technique
Lab Safety
Introductory Lab
Demo Simulation
Measurements and Uncertainty
Experimental Design
Light Microscopy
Microscopy
Aseptic Technique: Culture your sample without contamination
Counting Cells: Control the epidemic
Math for Scientists
Fundamental Mathematics: Density
Fundamental Mathematics: Logarithms and Exponentials
Fundamental Mathematics: Conversion factors and dimensional analysis
Fundamental Mathematics: Significant Figures
Scientific Notation: Converting large numbers
The Chemical Foundation of Life
Properties of Water
Atomic Structure: Assess the possibility of life on other planets
Biological Macromolecules
DNA: Structure and function
Biuret’s Test for Proteins
Protein Synthesis
Protein Denaturation
Sudan IV Test for Lipids
Benedict’s Test: Which food samples contain reducing sugars?
Iodine Test for Complex Carbohydrates
Benedict’s Test for Simple Carbohydrates
Carbohydrates: The sugars that feed us
Introduction to Food Macromolecules
Cell Structure
Gram Stain: How stains and counterstains work
Gram Stain: Test yourself in Gram Stain Procedure
Building Gram Positive and Gram Negative Cell Walls
The Gram Stain: Identify and differentiate bacteria
Bacterial Cell Structures: An introduction to the bacterial cell
Building Animal Cells
Cell Culture Basics: Plate, split and freeze human cells
Cell Structure: Cell theory and internal organelles
Structure and Function of Plasma Membranes
Cell Membrane and Transport: Types of transporter proteins
Cell Membrane and Transport: Modifying the cell membrane
Cell Membrane and Transport: Learn how transporters keep cells healthy
Metabolism
Enzyme Kinetics
Cellular Respiration (Principles): Measure energy consumption during exercise
Basic Chemistry Thermodynamics: Solve the challenge of storing renewable energy
Conservation of Energy (Principles): Unleash the roller coaster's potential
Cellular Respiration: Measuring energy consumption during exercise
Conservation of Energy: maximize the mechanical energy of a rollercoaster
Cellular Respiration
Cellular Respiration: The Krebs Cycle
Cellular Respiration: Glycolysis
Cellular Respiration: Respirometry
Cellular Respiration: Measuring energy consumption during exercise
Cellular Respiration (Principles): Measure energy consumption during exercise
Photosynthesis
Photosynthesis: Algae pigment analysis
Photosynthesis: Electron transport chain
Electron Transport Chain: A rollercoaster ride that produces energy
Cell Communication
Action Potential Lab: Experiment with a squid neuron
Signal Transduction: How cells communicate
Cell Reproduction
Cancer: Impact of BRCA mutations
Mitosis: Using a toxic compound from the yew tree in cancer therapy
Cell Division (Principles): Mitosis and Meiosis
Meiosis and Sexual Reproduction
Cell Division (Principles): Mitosis and Meiosis
Meiosis: Understand how traits are inherited
Mendel's Experiments and Heredity
Meiosis: How is color blindness inherited?
Inheritance with Punnett Squares
Inheritance with Pedigrees
Mendelian Inheritance: From genes to traits
Modern Understandings of Inheritance
Monogenic Disorders
Gene linkage and pedigree analyses
Medical Genetics
DNA Structure and Function
Molecular Cloning
Gene Expression Unit: Use sequencing to unveil a gene linked to obesity
DNA: Structure and function
Genes and Proteins
Introduction to Protein Synthesis
RNA Extraction: Sample and purify mRNA from pigs
Gene Expression
Cancer: Impact of BRCA mutations
Gene Regulation
Genetic Transfer in Bacteria: Prevent the rise of superbugs!
Biotechnology and Genomics
Invertebrate Model System: Find the genetic cause of a disease using C. elegans
Polymerase Chain Reaction
Embryology: Discover the genetics of limb development
Multiplex Automated Genomic Engineering (MAGE): Conjuring massive mutations
Biosafety
Fermentation: Optimize bio-ethanol production
Homogenization: Developing better-tasting milk
Molecular Cloning
CRISPR-Cas applied to TGF-beta induced EMT
Animal Genetics
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