General Biology I
Master the full spectrum of foundational biological concepts from the chemical and molecular basis of life to genetic engineering.
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Embark on an in-depth exploration into the building blocks of life. This course aims to equip students with an understanding of key biological concepts, from the chemical foundation of life to advanced topics in biotechnology and genomics. Through a series of interactive virtual simulations, students will analyze cellular structures, decipher metabolic pathways, and explore the mechanisms of gene expression and inheritance.
Investigating the Building Blocks of Life
Examine and differentiate the essential elements that constitute life, starting with the chemical foundations and biological macromolecules. Apply this knowledge and utilize virtual labs to reveal cellular structures and functions, which in turn, facilitate exploring complex, but essential, cellular processes such as respiration, photosynthesis, and division that power life.
Traverse the Path from DNA to Biotechnology
Walk the path that begins with Mendel’s Laws, the foundation of our knowledge of traits and inheritance. Assess Mendel’s experiments and extend this understanding to modern genetics, examining the structure and function of DNA, and the processes by which genes are expressed and proteins synthesized. Finally, apply theory in our genomics and biotechnology labs to see how genes and genetic processes can be leveraged to impact society and medicine.
Learning Objectives
- Illustrate and contextualize the chemical and molecular foundations of life
- Apply principles of metabolism, cellular respiration, and photosynthesis in energetic contexts
- Understand mechanisms of cell communication, reproduction, and genetic inheritance
- Evaluate advancements in biotechnology and genomics, considering their ethical, social, and practical implications
Browse Course Simulations by Unit
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The Study of Life
Counting Cells: Control the epidemic
Aseptic Technique: Culture your sample without contamination
Microscopy
Light Microscopy
Experimental Design
Measurements and Uncertainty
Demo Simulation
Introductory Lab
Lab Safety
Pipetting: Master the technique
Pipetting: Selecting and Using Micropipettes
Math for Scientists
Scientific Notation: Converting large numbers
The Chemical Foundation of Life
Atomic Structure: Assess the possibility of life on other planets
Properties of Water
Biological Macromolecules
Introduction to Food Macromolecules
Carbohydrates: The sugars that feed us
Benedict’s Test for Simple Carbohydrates
Iodine Test for Complex Carbohydrates
Benedict’s Test: Which food samples contain reducing sugars?
Sudan IV Test for Lipids
Protein Denaturation
Protein Synthesis
Biuret’s Test for Proteins
DNA: Structure and function
Cell Structure
Cell Structure: Cell theory and internal organelles
Cell Culture Basics: Plate, split and freeze human cells
Building Animal Cells
Bacterial Cell Structures: An introduction to the bacterial cell
The Gram Stain: Identify and differentiate bacteria
Building Gram Positive and Gram Negative Cell Walls
Gram Stain: Test yourself in Gram Stain Procedure
Gram Stain: How stains and counterstains work
Structure and Function of Plasma Membranes
Cell Membrane and Transport: Learn how transporters keep cells healthy
Cell Membrane and Transport: Modifying the cell membrane
Cell Membrane and Transport: Types of transporter proteins
Metabolism
Conservation of Energy: maximize the mechanical energy of a rollercoaster
Cellular Respiration: Measuring energy consumption during exercise
Conservation of Energy (Principles): Unleash the roller coaster's potential
Basic Chemistry Thermodynamics: Solve the challenge of storing renewable energy
Cellular Respiration (Principles): Measure energy consumption during exercise
Enzyme Kinetics
Cellular Respiration
Cellular Respiration (Principles): Measure energy consumption during exercise
Cellular Respiration: Measuring energy consumption during exercise
Cellular Respiration: Respirometry
Cellular Respiration: Glycolysis
Cellular Respiration: The Krebs Cycle
Photosynthesis
Electron Transport Chain: A rollercoaster ride that produces energy
Photosynthesis: Electron transport chain
Photosynthesis: Algae pigment analysis
Cell Communication
Signal Transduction: How cells communicate
Action Potential Lab: Experiment with a squid neuron
Cell Reproduction
Cell Division (Principles): Mitosis and Meiosis
Mitosis: Using a toxic compound from the yew tree in cancer therapy
Cancer: Impact of BRCA mutations
Meiosis and Sexual Reproduction
Meiosis: Understand how traits are inherited
Cell Division (Principles): Mitosis and Meiosis
Mendel's Experiments and Heredity
Mendelian Inheritance: From genes to traits
Inheritance with Pedigrees
Inheritance with Punnett Squares
Meiosis: How is color blindness inherited?
Modern Understandings of Inheritance
Medical Genetics
Gene linkage and pedigree analyses
Monogenic Disorders
DNA Structure and Function
DNA: Structure and function
Gene Expression Unit: Use sequencing to unveil a gene linked to obesity
Molecular Cloning
Genes and Proteins
RNA Extraction: Sample and purify mRNA from pigs
Introduction to Protein Synthesis
Gene Expression
Genetic Transfer in Bacteria: Prevent the rise of superbugs!
Gene Regulation
Cancer: Impact of BRCA mutations
Biotechnology and Genomics
Animal Genetics
CRISPR-Cas applied to TGF-beta induced EMT
Molecular Cloning
Homogenization: Developing better-tasting milk
Fermentation: Optimize bio-ethanol production
Biosafety
Multiplex Automated Genomic Engineering (MAGE): Conjuring massive mutations
Embryology: Discover the genetics of limb development
Polymerase Chain Reaction
Invertebrate Model System: Find the genetic cause of a disease using C. elegans
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