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About This Simulation
Analyze the microscopic structure of the small intestine and learn the advantages and limitations of light, fluorescence and electron microscopy.
Learning Objectives
- Understand different microscopy techniques and their limitations
- Identify various cell types and cellular structures
- Understand coeliac disease and intestinal inflammation
- Understand staining techniques
About This Simulation
Lab Techniques
- Fluorescence Microscopy
- Light microscopy: using immersion oil and working with different objectives
Related Standards
- Not directly assessed, could support many areas depending on educators approach
- Biology Unit 2: Cell Structure and Function
- 1.1 Introduction to cells*
- 1.2 Ultrastructure of cells
Learn More About This Simulation
Join the Microscopy lab and learn about the different types of microscopy to understand the mechanisms behind it. You will be trained in light microscopy, transmission electron microscopy and fluorescence microscopy.
Use magnification
In the Microscopy lab, you will be presented with chicken intestinal slides that have been stained with Anilin, Orange G and Fuchsin. Using the 5x magnification, you will identify the villus and then proceed with higher magnifications to identify smooth muscle, Relatedcellular tissue, epithelial cells, Goblet cells and the nuclei.
Try out the electron microscope
Electron microscopes can be used to visualize objects that are too small to see when using a light microscope—for example, the microvilli, mitochondria and the junctions between cells. In the Microscopy lab, you will examine a chicken intestine slide that is specially prepared for a transmission electron microscope. You can zoom in and out to observe different cellular structures.
Learn about fluorescence staining techniques
You will learn about fluorescence staining techniques and how they can be used to visualize specific structures. For example, by staining the DNA with DAPI, you can easily identify a cell’s nucleus. In this part of the lab, you will examine a chicken intestine sample that is infected with a retrovirus and observe how the virus infects the lymphocytes and how it inhibits inflammation. The retrovirus can be further developed as a medicine for coeliac disease.
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FAQs
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Labster can be integrated within a school's LMS (Learning Management System), and students can access it like any other assignment in their LMS. If your Institution does not choose an LMS integration, students will log in to Labster's Course Manager once they have an account created. Your institution will decide the access method during the sales process.
Labster is only available for purchase by faculty and administration at academic institutions. To procure Labster, simply reach out to us on our website. Schedule a demo, book a meeting to discuss pricing, start a free trial, or simply fill out our contact form.
Labster simulations are created by real scientists and designed with unparalleled interactivity. Unlike point and click competitors, Labster simulations immerse students and encourage mastery through active learning.
Labster supports a wide range of courses at the high school and university level across fields in biology, chemistry and physics. Some simulations mimic lab procedures with high fidelity to train foundational skills, while others are meant to bring theory to life through interactive scenarios.