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52
min

Nucleophilic Addition: Explore the Grignard Reaction | Virtual Lab

Assist scientists on a drug discovery project and learn how to use nucleophilic addition to transform organic molecules into life-saving drugs! Will you be able to synthesize a new pharmaceutical product using the Grignard reaction?
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Nucleophilic Addition: Explore the Grignard Reaction
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Simulation Details

Length:
52
Min
Level:
High School
Higher Education
Accessibility Mode:
No
Language:
English
Spanish
Italian
French
German

Learning Objectives

  • Demonstrate a detailed understanding of the nucleophilic addition reaction
  • Provide an overview and examples of nucleophilic addition to a carbonyl group
  • Draw correctly the mechanism for common nucleophilic addition reactions
  • Demonstrate a detailed understanding of the Grignard reaction
  • Describe the role of each reagent in the Grignard reaction
  • Explain the sensitivity of Grignard reaction conditions and be able to make procedural adjustments
  • Gain understanding and practical experience of essential laboratory techniques:

Skills Developed

Learners practice Laboratory Instruments & Methods, developing skills in performing titration, interpreting NMR, IR, and mass spectrometry results, conducting chromatography and PCR, and carrying out synthetic and sample preparation techniques.

Lab Techniques

  • Reflux technique
  • Synthesis and use of Grignard reagent in situ
  • Air- and moisture-sensitive synthesis
No lab techniques are listed for this simulation.

Related Standards

University:
NGSS:
  • No direct alignment
AP:
  • No direct alignment
IB:
  • No direct alignment
No related standards are listed for this simulation.

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What scientific skills does this simulation teach?
This simulation teaches:
Laboratory Instruments & Methods
Use common laboratory instruments and analytical methods.
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Does this simulation include Laboratory Instruments & Methods practice?

Yes, this simulation includes Laboratory Instruments & Methods by developing skills in performing titration, interpreting NMR, IR, and mass spectrometry results, conducting chromatography and PCR, and carrying out synthetic and sample preparation techniques.

What is a Labster virtual lab?

A Labster virtual lab is an interactive, multimedia assignment that students access right from their computers. Many Labster virtual labs prepare students for success in college by introducing foundational knowledge using multimedia visualizations that make it easier to understand complex concepts. Other Labster virtual labs prepare learners for careers in STEM labs by giving them realistic practice on lab techniques and procedures.

What types of courses does Labster support?

Labster supports a wide range of STEM courses at the high school, college, and university level across fields in biology, chemistry, physics, and health sciences. You can identify topics for your courses by searching our Content Catalog.

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