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About This Simulation
In the Nuclear Magnetic Resonance simulation, you will learn how to use NMR to characterize binding events between proteins and ligands. You will perform NMR experiments and interpret the resulting spectra. Will you be able to help improve an existing antibiotic in order to reduce its side effects?
Learning Objectives
- Understand how to perform NMR experiments
- Understand how to analyze NMR spectra
About This Simulation
Lab Techniques
- NMR
Related Standards
- No direct alignment
- No direct alignment
- No direct alignment
Learn More About This Simulation
Get your spin magnetized with NMR! In this simulation, you will learn about the nuclear magnetic resonance (NMR) technique from both a theoretical and practical perspective. In order to succeed, you will need to work with the instrument hands-on, preparing and running samples on it, and analyze the data.
Exploring protein-antibiotic interactions
Your mission will be to investigate how a common antibiotic may sometimes cause unwelcome side effects. After getting into the basics of how NMR works, you will explore how this antibiotic interacts with a protein in the kidneys, leading to kidney malfunction. Identifying the key interaction points is crucial in the work to improve the drug!
Running your own NMR samples
There are several distinct ways to use NMR. In your work in the virtual lab, we will discuss both isotope options, as well as 1-, 2- or 3-dimensional NMR. You will help decide which one is most suitable for the research questions we’re trying to answer. After preparing, loading and running your samples on the NMR instrument, you will need to interpret the produced spectra. Don’t worry, your lab assistant will be there to guide you!
Side effects that keep people sick
To complete your mission, you will have to understand the aspects of NMR well enough to identify the key interaction points between the kidney protein and the antibiotic so we can look into modifying these sites and avoid the interaction.
Will you be able to help reduce the side effects of this drug?
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Related Course
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For Science Programs Providing a Learning Advantage
North Dakota State College of Science
“They did the simulation at home, then completed the in-person lab within 30 minutes, no questions asked, and passed the quiz with flying colors.”
Lecturer in Human Physiology
University of Westminster
"I saw some of the students who clearly didn’t necessarily like sitting there reading a book discover they could turn on Labster and keep up with the rest of the class because it spoke to them.
Modesto City Schools
"Having something that's engaging for the students gives teachers that opportunity to breathe and get excited again. Because they're seeing the kids light up, they're seeing the kids engage with content."
Wenatchee Valley College
"The question always is, ‘Can we demonstrate that the students are meeting course outcomes?’ Check! We can do that.”
San José State University
"We surveyed over 400 students. More than 90% thought Labster was easy to navigate, and that it was fun, but more importantly, most of them felt confident that they could execute the labs in person. And that confidence is a big deal."
FAQs
Find answers to frequently asked questions.
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Labster can be integrated within a school's LMS (Learning Management System), and students can access it like any other assignment in their LMS. If your Institution does not choose an LMS integration, students will log in to Labster's Course Manager once they have an account created. Your institution will decide the access method during the sales process.
Labster is only available for purchase by faculty and administration at academic institutions. To procure Labster, simply reach out to us on our website. Schedule a demo, book a meeting to discuss pricing, start a free trial, or simply fill out our contact form.
Labster simulations are created by real scientists and designed with unparalleled interactivity. Unlike point and click competitors, Labster simulations immerse students and encourage mastery through active learning.
Labster supports a wide range of courses at the high school and university level across fields in biology, chemistry and physics. Some simulations mimic lab procedures with high fidelity to train foundational skills, while others are meant to bring theory to life through interactive scenarios.